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个人简历
教育经历
1993 - 1996 , 工学博士 , 应用化学 , 北京理工大学
1990 - 1993 , 理学硕士 , 物理化学 , 吉林大学
1986 - 1990 , 理学学士 , 有机化学 , 辽宁大学
1990 - 1993 , 理学硕士 , 物理化学 , 吉林大学
1986 - 1990 , 理学学士 , 有机化学 , 辽宁大学
工作经历
2000 - 至今 , 副教授 , 北京大学生命科学学院
1998 - 2000 , 讲师 , 北京大学生命科学学院
1996 - 1998 , 博士后 , 军事医学科学院药物与毒物研究所
1998 - 2000 , 讲师 , 北京大学生命科学学院
1996 - 1998 , 博士后 , 军事医学科学院药物与毒物研究所
教材编撰
实用生物统计(第2版), 李松岗、曲红编, 北大出版社, 2007
科研领域描述
1. 利用泛癌基因组数据整合分析复杂疾病中的遗传机制;
2. 构建和拓扑分析代谢转运网络;
3. 计算模拟分析生物大分子的结构和功能;
4. 研究circular RNA作为竞争性内源RNA在癌症转移中的调控作用
2. 构建和拓扑分析代谢转运网络;
3. 计算模拟分析生物大分子的结构和功能;
4. 研究circular RNA作为竞争性内源RNA在癌症转移中的调控作用
代表性论文
1. Liu Y, Zhao M*, Hong Qu*. 2023. Identification of cytokine-induced cell communications by pan-cancer meta-analysis. PeerJ 11:e16221. https://doi.org/10.7717/peerj.16221.
2. Liu T, Liu Y, Su X, Peng L, Chen J, Xing P, Qiao X, Wang Z, Di J, Zhao M*, Jiang B*, Hong Qu*. Genome-wide transcriptomics and copy number profiling identify patient-specific CNV-lncRNA-mRNA regulatory triplets in colorectal cancer. Comput Biol Med. 2023 Feb;153:106545. doi: 10.1016/j.compbiomed.2023.106545. Epub 2023 Jan 11. PMID: 36646024.
3. Peng L, Zhao M, Liu T, Chen J, Gao P, Chen L, Xing P, Wang Z, Di J, Xu Q, Hong Qu*, Jiang B*, Su X*. A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway. Cell Death Dis. 2022 Apr 22;13(4):395. doi: 10.1038/s41419-022-04844-3.
4. Liu Y, Chen L, Liu T, Su X, Peng L, Chen J, Tan F, Xing P, Wang Z, Di J, Jiang B*, Hong Qu*. Genome-wide circular RNA (circRNA) and mRNA profiling identify a circMET-miR-410-3p regulatory motif for cell growth in colorectal cancer. Genomics. 2022 Jan;114(1):351-360. doi: 10.1016/j.ygeno.2021.11.038.
5. Zhao M, Liu Y, Hong Qu*. circExp database: an online transcriptome platform for human circRNA expressions in cancers. Database (Oxford). 2021 Jul 23;2021:baab045. doi: 10.1093/database/baab045.
6. Zhao M, Liu Y, Ding G, Qu D*, Hong Qu*. Online database for brain cancer-implicated genes: exploring the subtype-specific mechanisms of brain cancer. BMC Genomics. 2021 Jun 18;22(1):458. doi: 10.1186/s12864-021-07793-x.
7. Min Zhao, Hong Qu*, circVAR database: genome-wide archive of genetic variants for human circular RNAs. BMC Genomics. 2020 Oct 29; 21(1): 750. doi: 10.1186/s12864-020-07172-y.
8. Min Zhao, Yining Liu, Chong Zheng, Hong Qu*, dbEMT 2.0: An updated database for epithelial-mesenchymal transition genes with experimentally verified information and precalculated regulation information for cancer metastasis, Journal of Genetics and Genomics, 2019 Dec 20;46(12):595-597.
9. Haokai Sang, Shuli Guo, Hong Qu*, Min Zhao*, and Dacheng Qu*, Development of omics data based survival models for four female cancers using machine learning approaches. Sci Sin Vitae, 2019, 49, doi: 10.1360/N052018-00265.
10. Yining Liu, Mingyu Luo, Qijun Li, Jiachun Lu, Min Zhao*, and Hong Qu*, CIGene: a literature-based online resource for cancer initiation genes. BMC Genomics. 2018; 19: 552.
11. Yining Liu, Mingyu Luo, Zhaochen Jin, Min Zhao*, and Hong Qu*, dbLGL: an online leukemia gene and literature database for the retrospective comparison of adult and childhood leukemia genetics with literature evidence. Database (Oxford). 2018. doi: 10.1093/database/bay062.
12. Yining Liu, Zhe Li, Jiachun Lu, Min Zhao*, Hong Qu*. CMGene: A literature-based database and knowledge resource for cancer metastasis genes. J Genet Genomics. 44(5):277-279 (2017)
2. Liu T, Liu Y, Su X, Peng L, Chen J, Xing P, Qiao X, Wang Z, Di J, Zhao M*, Jiang B*, Hong Qu*. Genome-wide transcriptomics and copy number profiling identify patient-specific CNV-lncRNA-mRNA regulatory triplets in colorectal cancer. Comput Biol Med. 2023 Feb;153:106545. doi: 10.1016/j.compbiomed.2023.106545. Epub 2023 Jan 11. PMID: 36646024.
3. Peng L, Zhao M, Liu T, Chen J, Gao P, Chen L, Xing P, Wang Z, Di J, Xu Q, Hong Qu*, Jiang B*, Su X*. A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway. Cell Death Dis. 2022 Apr 22;13(4):395. doi: 10.1038/s41419-022-04844-3.
4. Liu Y, Chen L, Liu T, Su X, Peng L, Chen J, Tan F, Xing P, Wang Z, Di J, Jiang B*, Hong Qu*. Genome-wide circular RNA (circRNA) and mRNA profiling identify a circMET-miR-410-3p regulatory motif for cell growth in colorectal cancer. Genomics. 2022 Jan;114(1):351-360. doi: 10.1016/j.ygeno.2021.11.038.
5. Zhao M, Liu Y, Hong Qu*. circExp database: an online transcriptome platform for human circRNA expressions in cancers. Database (Oxford). 2021 Jul 23;2021:baab045. doi: 10.1093/database/baab045.
6. Zhao M, Liu Y, Ding G, Qu D*, Hong Qu*. Online database for brain cancer-implicated genes: exploring the subtype-specific mechanisms of brain cancer. BMC Genomics. 2021 Jun 18;22(1):458. doi: 10.1186/s12864-021-07793-x.
7. Min Zhao, Hong Qu*, circVAR database: genome-wide archive of genetic variants for human circular RNAs. BMC Genomics. 2020 Oct 29; 21(1): 750. doi: 10.1186/s12864-020-07172-y.
8. Min Zhao, Yining Liu, Chong Zheng, Hong Qu*, dbEMT 2.0: An updated database for epithelial-mesenchymal transition genes with experimentally verified information and precalculated regulation information for cancer metastasis, Journal of Genetics and Genomics, 2019 Dec 20;46(12):595-597.
9. Haokai Sang, Shuli Guo, Hong Qu*, Min Zhao*, and Dacheng Qu*, Development of omics data based survival models for four female cancers using machine learning approaches. Sci Sin Vitae, 2019, 49, doi: 10.1360/N052018-00265.
10. Yining Liu, Mingyu Luo, Qijun Li, Jiachun Lu, Min Zhao*, and Hong Qu*, CIGene: a literature-based online resource for cancer initiation genes. BMC Genomics. 2018; 19: 552.
11. Yining Liu, Mingyu Luo, Zhaochen Jin, Min Zhao*, and Hong Qu*, dbLGL: an online leukemia gene and literature database for the retrospective comparison of adult and childhood leukemia genetics with literature evidence. Database (Oxford). 2018. doi: 10.1093/database/bay062.
12. Yining Liu, Zhe Li, Jiachun Lu, Min Zhao*, Hong Qu*. CMGene: A literature-based database and knowledge resource for cancer metastasis genes. J Genet Genomics. 44(5):277-279 (2017)
执教课程
生物统计 , 主讲 , 北京大学 , 2003-今
计算概论 , 主讲 , 北京大学 , 1999-2003
计算概论 , 主讲 , 北京大学 , 1999-2003
